Drug stability for pharmaceutical scientists pdf

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drug stability for pharmaceutical scientists pdf

A Critical Appraisal of Drug Stability Testing Methods | SpringerLink

Drug Stability for Pharmaceutical Scientists is a clear and easy-to-follow guide on drug degradation in pharmaceutical formulation. This book features valuable content on both aqueous and solid drug solutions, the stability of proteins and peptides, acid-base catalyzed and solvent catalyzed reactions, how drug formulation can influence drug stability, the influence of external factors on reaction rates and much more. Full of examples of real-life formulation problems and step-by-step calculations, this book is the ideal resource for graduate students, as well as scientists in the pharmaceutical and related industries. Chapter 2 Principles of Drug Degradation In this chapter, the kinetics of drug degradation is reviewed, and it is shown how various excipients, such as buffer salts and complexing agents, the phase distribution of the drug such as in suspensions and emulsions, and external factors such as temperature, oxygen, and light, can influence reaction rates. It is shown how the shelf-life of drug products can be enhanced through proper formulation. The chapter contains numerous practical examples of how various equations and theories are used to solve problems encountered during drug stability testing. The rate of reaction may be defined as the rate of concentration changes of the reactants or products:.
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Calculation of expiry date (shelf-life) of medicine by accelerated stability study method in english

Drug Stability for Pharmaceutical Scientists (eBook)

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2.2 First-Order Reactions

Cookie policy : This site uses cookies small files stored on your computer to simplify and improve your experience of this website. Cookies are small text files stored on the device you are using to access this website. For more information please take a look at our terms and conditions. Some parts of the site may not work properly if you choose not to accept cookies. During her time as a researcher, Emma authored more than 30 papers, abstracts, and book chapters and co-authored a book. A love of science communication and writing prompted a move into the Medical Communications industry. This short handbook describes the concepts of drug stability and degradation.

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