Principles of Virology, Volume I: Molecular Biology, 3rd Edition
The second edition retains all of the defining and much—praised features of the first edition, focusing on concepts and principles and presenting a comprehensive treatment from molecular biology to pathogenesis and infection control. Written in an engagingly readable style and generously illustrated with over full—color illustrations, this approachable volume offers detailed examples that illustrate common principles, specific strategies adopted by different viruses to ensure their reproduction, and the current state of virology research. The book is divided into chapters that focus on specific topics rather than individual viruses, and allows the student to visualize common themes that cut across virus families, emphasizing the shared features of different viruses. Drawing on the extensive teaching experience of each of its distinguished authors, Principles of Virology illustrates why and how animal viruses are studied and demonstrates, using well—studied systems, how the knowledge gained from such model viruses can be used to study viral systems about which our knowledge is still quite limited. A thorough introduction to principles of viral pathogenesis, a broad view of viral evolution, a discussion of how viruses were discovered, and how the discipline of virology came to be are also provided. A variety of special boxes highlight key experiments, background material, caveats, and much more. The text focuses on concepts and principles and covers not only aspects of molecular biology, but also pathogenesis, evolution, emergence, and control, and will also be a valuable resource for practicing physicians and scientists.
The basic thesis of the course is that all viruses adopt a common strategy. The strategy is simple:. Genomes encode gene products that promote an infectious cycle mechanisms for genomes to enter cells, replicate, and exit in particles. Infection patterns range from benign to lethal; infections can overcome or co-exist with host defenses. Despite the apparent simplicity, the tactics evolved by particular virus families to survive and prosper are remarkable. Virology has enabled a more detailed understanding of the structure and function of molecules, cells and organisms and has provided fundamental understanding of disease and virus evolution. The course will emphasize the common reactions that must be completed by all viruses for successful reproduction within a host cell and survival and spread within a host population.
10 editions of this work
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I am pleased to announce the publication by ASM Press of the fourth edition of our virology textbook, Principles of Virology. Two years in the making, this new edition is fully updated to represent the rapidly changing field of virology. Studying the phases of the viral reproductive cycle, illustrated with a set of representative viruses, provides an overview of the steps required to maintain these infectious agents in nature. Such knowledge cannot be acquired by learning a collection of facts about individual viruses. Consequently, the major goal of this book is to define and illustrate the basic principles of animal virus biology. This edition is marked by a change in the author team. Our new member, Glenn Rall, has brought expertise in viral immunology and pathogenesis, pedagogical clarity, and down-to-earth humor to our work.